BDBM384368 US10590114, No. 54B::US11111235, No. 54B::US11591316, Compound 54B::US9932325, Example 54A::US9932325, Example 54B

SMILES CCNc1nc(Nc2cnn3CC(Cc23)n2nccn2)ncc1C(F)(F)F

InChI Key InChIKey=JZUKWWQGMGJGRD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 384368   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Denali Therapautics

US Patent
LigandPNGBDBM384368(US10590114, No. 54B | US11111235, No. 54B | US1159...)
Affinity DataIC50: <30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Denali Therapautics

US Patent
LigandPNGBDBM384368(US10590114, No. 54B | US11111235, No. 54B | US1159...)
Affinity DataIC50: <30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent